BioDot :: Applications :: BioSensor

BioSensor: Glucose

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Following advances in microelectronics, and biosensor designs are becoming increasingly complex, and focused on miniaturization. The demand for simultaneous measurement of multiple analytes has stimulated development of high density arrays. As a result of this demand, and the advancing capabilities of patterning technologies, research and development programs aimed at sensor arrays containing multiple biomarkers in devices on the order of a square centimeter are underway. Fabrication of these devices typically requires reagent-dispensing approaches capable of delivering volumes ranging from the low microliters to picoliters. Reductions in volume reduce cost of expensive reagents, increase surface dependant reaction rates, and promote adoption of multiplexed diagnostic devices. Dispensing systems used must be compatible with a wide range of reagent classes, including organic solvents, biological fluids, polymeric solutions, as well as the traditional combination of buffer and enzymes. Systems must be robust enough to produce hundreds of thousands to millions of dispenses with a high level of precision and accuracy. Lastly these systems must function in a production environment using less skilled labor and also subject to rigorous regulatory requirements.

The Glucose biosensor is probably the most common of biosensors where the typical format is a “sheet” and the reagent is dispensed to a pre-printed electrode pattern. In many biosensor applications, multiple layers of different samples are dispensed in different steps, requiring great flexibility as well as high positional accuracy. The sample is allowed to dry down and then is cut, and packaged.

Additional Information ...

An overview of the complex BioSensor designs, bringing efficiency to the microelectronics field. Rapid growth in the field of microelectronics has bought complex BioSensor designs, in order to bring efficiency in this field. Perhaps, the demand for multiple analysts is also taking turn in order to stimulate high density arrays. Patterning technologies are also making progress along with lot of research and development programs at sensor arrays which contain multiple biomarkers and the work is under full swing. Regent-dispensing approach is very much required at the time fabrication of these devices while delivering volumes right from low micro liters to pico liters. While maintaining the great accuracy, volume reduction may reduce expensive reagents cost and enhances reaction rate.

BioDot’s slitting module uses automatic technology in order to cut sheet material into pieces with shorter width. This robust module is programmed through company’s handheld terminal used to take number of cuts with speed. The programming has been done in such a way that every program gets saved for future reference. Required production speed can be achieved with the help of various blades, which is a best part of this slitter design. This user-friendly module is designed with convenient feed system, quite operation and also provides an ease in cleaning blades. The most common biosensor which is Glucose BioSensor is a typical format in which the sheet and regent is dispensed to an electrode pattern which will in the form of pre-printing. Usually in various applications of BioSensor different samples are dispensed in various steps, which generally require high positional accuracy and great flexibility. Then the process of sample cutting will be followed after the drying and then final packaging will complete the process.

Typical process of BioSensor includes:

Allot to BioSensor substrate
Dry
Assemble and laminate all the components of test
Singulate or cut the tests
Package

The basic function of this machine is to take large cuts of material and slits into different lengths and widths, which will meet the ultimate requirements of the design. While doing so, number of modes of operation will be carried out in order to take the cuts. BioDot manufacturer’s laboratory has plenty of wide experience in the field of manufacturing. Extensive cutting-edge technology, with an extensive portfolio including biologics, engages them with their clients.

Fabulous technical support catered by BioDot is the effort taken by the available integrated team members and their work towards a common goal in order to provide efficient installations and high-performance systems. To ensure better system reliability and its performance, the program of scheduled preventive maintenance is available, which includes cleaning, inspection and calibration of the instruments. Every customer will be catered by the complete support system, right from the installation to the handling. At the time of agreement, fixed service cost will be offered and we always stick to the terms and conditions mentioned in the agreement. For adopting the various techniques and equipments available with BioDot, may sometimes require technical support. In order to serve customer need application laboratories are available in Europe, Asia and North America serves your purpose in a better way.

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