Application
Lyobead
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The Lyobead manufacturing process begins with bead creation – the dispensing and freezing of liquid, reagent, or drug using technologies that deliver singulated beads of the desired size and shape. BioDot’s platform design expertise applied to the Lyobead formation challenge resulted in the established new Sphera™ discrete dispensing technology.
Sphera™ Technology
- Superior Performance
- Better Yield
- Higher Throughput
- Expanded Dynamic Range
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Sphera™ Lyobead Dispensing Platform
BioDot's Sphera Technology offers turn-key solutions for LyoBead production that include a bead dispenser, sealable tray, and freeze dryer. The combination provides all the necessary parts to quickly implement using Lyobeads
- 2μL- 30μL Automated Spherical Lyobead formation
- 7,000-60,000 beads per hour
- In-Process Bead Volume Tuning
Sphera Lyobead
Lyobead
System
Dispense Channels
Mode / Process
Substrates
Dispense Area / Capacity
System Control
Dispense Technology
Options
Sphera™ Discovery
1
Small-scale dispensing/ Beads and Spheres
Freezing beads in liquid nitrogen containers
X~400mm
Y~200mm
Z~100mm
Six (06) 12-oz double-wall, vacuum-insulated stainless-steel containers
BioDot Studio
BioJet Syringe Pump
Tip selection and geometry / Collection Container / Reagent temperature control
Sphera™
1-4
Bulk Dispense / Beads and Spheres
Freezing beads in liquid nitrogen bath
Dispense area in bath: X ~315mm (dependent on number of channels) / Y=250mm. 240 partition holes, 13mm hole D / 15mm pitch / Bead dispensing 10,000 – 40,000
BioDot Studio
BioJet PN
Tip selection and geometry / Can use own partition / Reagent temperature control
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